_____ Brought to you by Wyatt Technology _____
Understanding Phase Separation in Hydrogel Microparticles via Complementary Light Scattering and Microscopy Tools
September 17, 2019
8:00 a.m. PDT,
11:00 a.m. EDT,
16:00 BST, 17:00 CEST
This webinar will present the use of dynamic light scattering (DLS), electrophoretic light scattering (ELS), and various microscopy methods to understand pH and pH- and temperature-triggered swelling transitions in a unique class of "ultra-low-cross-linked" hydrogel microparticles. An introduction to dynamic light scattering and phase-analysis light scattering will be provided as well.
The complex interplay between thermally-driven polymer phase separation, charge segregation, and nanostructure evolution present a set of particularly difficult characterization challenges that are overcome by employing a suite of complementary yet orthogonal analytical tools. Given the potential utility of this class of materials for a wide range of applications in biotechnology, obtaining a deep level of insight into their properties is of paramount importance when considering efficacy, safety, and overall materials performance.
Brought to you by:
Analysis of micro- and nano- phase separation events occurring in microparticles during volume phase transitions
- Basics of dynamic and electrophoretic light scattering, technology and applications.
- DLS size analysis of hydrogel microparticles
- ELS for electrophoretic mobility determination
- Size and morphology analysis via atomic force microscopy
- Researchers interested in exploring DLS/ELS/AFM for soft materials analysis
- Researchers interested in understanding more about hydrogel microparticles, their characterization, and potential applications
Professor Andrew Lyon,
Dean of Fowler School of Engineering,
Dr. Jason Lin,
Wyatt Technology Corporation