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Drug Delivery

Spotlight Therapeutics raises $30 million in vivo CRISPR gene editing

by Ryan Cross
December 5, 2020 | A version of this story appeared in Volume 98, Issue 47
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Most Popular in Pharmaceuticals

 

Spotlight Therapeutics has raised $30 million in series A financing to develop CRISPR gene-editing therapies for genetic blood diseases and cancer. Spotlight attaches antibodies, cell-penetrating peptides, or ligands to a CRISPR ribonucleoprotein—a guide RNA paired with a nuclease like Cas9—to shuttle the gene-editing system to particular cells in the body. Other CRISPR firms rely on lipid nanoparticles or viral vectors for delivery. The start-up was quietly cofounded in 2018 by gene-editing scientists Alex Marson, Jacob Corn, and Patrick Hsu.

Chemical & Engineering News
ISSN 0009-2347
Copyright © 2024 American Chemical Society

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