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Drug Development

AstraZeneca licenses small-molecule heart drug from China’s CSPC

by Sarah Braner
October 20, 2024 | A version of this story appeared in Volume 102, Issue 33

 

AstraZeneca has licensed a small-molecule lipoprotein disruptor from China’s CSPC Pharmaceutical Group for $100 million. The molecule is intended to prevent formation of lipoprotein(a), high concentrations of which are thought to contribute to heart disease. AstraZeneca says the molecule could be used for multiple cardiovascular diseases and may be combined with AZD0780, a PCSK9 inhibitor it is developing to treat high lipid levels. CSPC could reap up to $1.92 billion in milestone payments.

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