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Drug Discovery

Terns buys Lilly liver disease compounds

by Lisa M. Jarvis
April 9, 2018 | A version of this story appeared in Volume 96, Issue 15
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Eli Lilly & Co. has sold Terns Pharmaceuticals the rights to three small-molecule drug candidates for nonalcoholic steatohepatitis (NASH), a liver disease. The biotech firm is gaining a farnesoid X receptor agonist, a semicarbazide-sensitive amine oxidase inhibitor, and a preclinical molecule against an undisclosed drug. Terns will first develop the compounds in China. No drugs are approved to treat NASH, which is estimated to afflict up to 5% of the world’s population.

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