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Gene Therapy

Chroma Medicine launches with $125 million for epigenetic editing

by Ryan Cross
November 21, 2021 | A version of this story appeared in Volume 99, Issue 42
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Chroma Medicine has launched with $125 million in financing to develop ­epigenetic editing therapies. Chroma uses a version of CRISPR gene editing that turns genes on or off by changing methylation patterns on DNA rather than by changing the DNA code itself. “We think it is going to unlock a huge breadth of applications,” says CEO Catherine Stehman-Breen. The firm isn’t disclosing its lead programs. Chroma is based on the work of its six academic founders: Luke Gilbert, Keith Joung, David Liu, Angelo Lombardo, Luigi Naldini, and Jonathan Weissman.

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