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Pharmaceutical Chemicals

Manus Bio gets Gates grant for artemisinin

by Melody M. Bomgardner
April 9, 2021 | A version of this story appeared in Volume 99, Issue 13

The chemical structure of artemisinin is shown.

Manus Bio has received an undisclosed sum from the Bill and Melinda Gates Foundation to develop a cost-effective way to produce artemisinin, a malaria treatment, via fermentation. The foundation has set a target cost for the treatment of $100 per kilogram. Artemisinin is currently derived from plants; Manus, one of C&EN’s 10 Start-Ups to Watch in 2018, will use engineered microbes and enzymes to produce the compound. Manus also received a grant from the Gates foundation in 2018.

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