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Vaccines

Gritstone advances COVID-19 vaccine

by Laura Howes
October 6, 2023 | A version of this story appeared in Volume 101, Issue 33
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The US Biomedical Advanced Research and Development Authority (BARDA) has given California biotechnology firm Gritstone Bio a contract to advance the firm’s next-generation COVID-19 vaccine candidate. The vaccine is based on self-amplifying messenger RNA (samRNA) that encodes the SARS-CoV-2 spike protein and other viral targets. The contract is worth up to $433 million. Gritstone will use the cash to conduct a Phase 2b trial comparing its vaccine with an approved COVID-19 vaccine.

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