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Volume 85 Issue 49 | p. 11 | News of The Week
Issue Date: December 3, 2007

Probing Large Protein Systems

Approach yields first detailed analysis of 456-protein nuclear pore complex
Department: Science & Technology | Collection: Life Sciences
NUCLEAR PORE COMPLEX
Movie shows that the nuclear pore complex is composed of protein-based substructures of various types???outer rings, inner rings, membrane rings, linker nucleoporins, and FG (phenylalanine-glycine) nucleoporins. Pore membrane is gray.
Credit: Created by Frank Alber
Some Assembly Required
Protein-based substructures???outer rings (yellow), inner rings (purple), membrane rings (brown), linker nucleoporins (green), and FG (phenylalanine-glycine) nucleoporins???make up the nuclear pore complex (center). Pore membrane is gray.
Credit: Nature © 2007
8549notw1_complexcxd
 
Some Assembly Required
Protein-based substructures???outer rings (yellow), inner rings (purple), membrane rings (brown), linker nucleoporins (green), and FG (phenylalanine-glycine) nucleoporins???make up the nuclear pore complex (center). Pore membrane is gray.
Credit: Nature © 2007

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