Issue Date: October 27, 2008
Streamlined Stem Cell Recipe
A dash of valproic acid eliminates the need for two of the four genes used to reprogram adult human cells into stem cells (Nat. Biotechnol., DOI: 10.1038/nbt.1502). This is the first human stem cell recipe to require the insertion of only two genes, a significant step toward an entirely chemical cocktail for cell reprogramming. Researchers would like to avoid relying on gene additions to make stem cells from adult cells because the genes become integrated . . .
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