Issue Date: April 6, 2009
Blocking Brain Hormone Receptor Curbs Addiction . . .
New findings about a natural appetite stimulant produced in the brain—melanin-concentrating hormone (MCH)—might lead to a novel pathway for treating drug addiction (Proc. Natl. Acad. Sci. USA, DOI: 10.1073/pnas. 0811331106). A large amount of the hormone's receptor, MCH1R, is found in a brain region that helps control behaviors associated with reward and motivation. So Olivier Civelli of the University of California, Irvine, reasoned that MCH and its receptor might participate in addiction. In . . .
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