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Volume 87 Issue 41 | p. 43 | Concentrates
Issue Date: October 12, 2009

Microfluidic Assay For Estrogen

A droplet-based digital microfluidic device measures estradiol in breast tissue with as little as 1 µL of sample–and shortens analysis time
Department: Science & Technology
Keywords: digital microfluidics, estrogen, clinical assays

Measuring estrogen levels in breast tissue can be used to identify women at high risk for breast cancer or to monitor the effects of breast cancer therapy. However, the standard methods available are impractical because they require large amounts of tissue. Aaron R. Wheeler, Robert F. Casper, and coworkers of the University of Toronto have now developed a miniaturized, automated, and integrated method using droplet-based digital microfluidics (DMF) to measure estrogen in 1-µL . . .

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