Issue Date: November 8, 2010
Amyloid Fibrils Grow Asymmetrically
Structural models have predicted that amyloid fibrils, which are associated with and may help cause conditions such as Alzheimer’s disease, grow symmetrically at both ends. Caryn L. Heldt, Shuqi Zhang, and Georges Belfort at Rensselaer Polytechnic Institute have put those models to the test and found them wanting (Proteins: Struct., Funct., Bioinf., DOI: 10.1002/prot.22861). The researchers attached different fluorescent dyes to the protein insulin, which forms amyloid, and to insulin-based fibrils. . . .
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