Issue Date: April 23, 2012
Common Antibiotic Mechanism Shown
Guanine oxidation is at the heart of the cell-killing abilities of many common antibiotics, biologists at MIT and Boston University report (Science, DOI: 10.1126/science.1219192). The findings, if confirmed, could improve scientists’ understanding of the way existing antibiotics actually work.
Previously, James J. Collins and coworkers at Boston University reported that diverse antibiotics with different targets have a common cell-killing mechanism (C&EN, . . .
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