Volume 91 Issue 7 | p. 42 | Concentrates
Issue Date: February 18, 2013

X-ray Pulses Yield Protein And Metal Data

Femtosecond technique reveals structure and metal state of metalloproteins
Department: Science & Technology
News Channels: Analytical SCENE, Biological SCENE
Keywords: X-ray, diffraction, X-ray emission spectroscopy, photosystem II, protein dynamics, metalloprotein

The study of metal-containing proteins, such as the complex that mediates the light reaction in photosynthesis, has a new tool: Femto­second X-ray pulses facilitate simultaneous diffraction and spectroscopy analyses of metalloproteins, enabling study of radiation-sensitive, difficult-to-crystallize systems at room temperature (Science, DOI: 10.1126/science.1234273). The approach will promote time-resolved chemical dynamics studies of metalloproteins, say research team leaders Vittal K. Yachandra and Junko Yano of Lawrence Berkeley . . .

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