Volume 92 Issue 32 | p. 8 | News of The Week
Issue Date: August 11, 2014

MicroRNA Levels Indicate Acetaminophen Poisoning In Blood Tests

Panel of 11 microRNAs bests a conventional biomarker in small group of patients
Department: Science & Technology
News Channels: Analytical SCENE, Biological SCENE
Keywords: acetaminophen, overdose, microRNAs, PCR

When doctors in the emergency room suspect that a patient has overdosed on the popular painkiller acetaminophen, they want to verify the diagnosis quickly before liver damage sets in. But that’s not always possible.

Now researchers report a group of 11 biomarkers that, if validated in large groups of patients, might be a rapidly detectable signature of acetaminophen poisoning and a sensitive indicator that emergency treatment is working (Proc. Natl. Acad. Sci. USA 2014, DOI: . . .

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