Volume 92 Issue 5 | p. 8 | News of The Week
Issue Date: February 3, 2014 | Web Date: January 30, 2014

Enzyme Makes Tough-To-Construct C–N Bonds

Chemical Biology: Halogenase directly adds nitrite or azide to unactivated aliphatic carbons
Department: Science & Technology
News Channels: Biological SCENE, Organic SCENE
Keywords: nitration, azidation, enzyme

The ability to add nitrogen-containing functional groups to unactivated aliphatic carbon atoms is a challenge for synthetic chemists. The search for enzymes to catalyze such reactions has likewise come up empty-handed. That luck, however, might be about to change.

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