Volume 92 Issue 6 | p. 27 | Concentrates
Issue Date: February 10, 2014

Antibody-Loving Protein Binds Around

Newly discovered bacterial protein binds a cornucopia of antibodies, a property that could be leveraged to help purify the antibodies
Department: Science & Technology | Collection: Life Sciences
News Channels: Biological SCENE, Environmental SCENE
Keywords: antibody, pathogen, immune system

A wildly promiscuous protein produced by pathogenic Mycoplasma, such as those that cause genital and respiratory tract infections, appears to have the ability to bind any antibody it encounters—including those from humans, mice, rabbits, pigs, and goats. In doing so, the protein covers up the variable section of the antibodies, preventing them from hooking up with their intended targets (Science 2014, DOI: 10.1126/science.1246135). . . .

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