Issue Date: February 10, 2014
Directed Evolution Keeps Pace
A technique that enables proteins to be evolved in the lab in a continuous manner without user intervention has proven useful in creating proteins with new properties. Now, the researchers who devised the technique have added capabilities that expand the method’s utility.
Phage-assisted continuous evolution (PACE), first developed in 2011 by David R. Liu and coworkers at Harvard University, harnesses the rapid life cycle of bacteria-infecting viruses called bacteriophages to enable rapid . . .
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