Volume 93 Issue 24 | p. 8 | News of The Week
Issue Date: June 15, 2015 | Web Date: June 11, 2015

Enzyme Inhibitor Helps Tissue Heal In Mice

Drug Discovery: Small molecule blocks the breakdown of key prostaglandin to promote cell proliferation
Department: Science & Technology
News Channels: Biological SCENE, Organic SCENE
Keywords: tissue regeneration, prostaglandin

A newly identified small molecule increases the rate of tissue regeneration in the colon, liver, and bone marrow of mice. With further testing and development, such a compound could lead to therapies that would help patients heal tissues damaged by disease or excised through surgery.

In previous studies on animals or patients, scientists have tried to accelerate tissue and blood cell growth by administering analogs of prostaglandin E2 (PGE2), a lipid that promotes regeneration by . . .

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