Volume 94 Issue 13 | p. 9 | Concentrates
Issue Date: March 28, 2016

Mechanism-based screening accelerates photocatalysis research

Novel strategy could become a useful tool in the hunt for compound classes and catalysts to employ in new chemical reactions
Department: Science & Technology
News Channels: Organic SCENE
Keywords: synthesis, reaction mechanisms, catalysis, high-throughput screening, photocatalysis

Screening strategies to discover new catalysts or types of reactions typically count hits by the number of new products that turn up in crude reaction mixtures. Frank Glorius and colleagues of the University of Münster have decided to try a different approach: They only screen molecules for their ability to take part in a single step of a reaction. If an interaction occurs, the molecule is considered a hit. What’s more, . . .

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