Issue Date: April 18, 2016 | Web Date: April 14, 2016
New close-up views of the nuclear pore complex
As gatekeeper of the cell’s nucleus, the nuclear pore complex (NPC) controls the shuttling of thousands of different proteins, RNA molecules, and nutrients between the nucleus and surrounding cytoplasm. Built from more than 30 types of nucleoporin proteins, and with a mass of more than 100 million daltons and a width of 1,000 Å, the NPC’s gargantuan, membrane-embedded structure has long stymied structural biologists.
Two research teams working independently have now reported the overall architecture . . .
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- Chemical & Engineering News
- ISSN 0009-2347
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