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Copyright © 2010 American Chemical Society
April 5, 2010 Cover
Volume 88, Issue 14
COVER: The brains of people with Alzheimer's disease are riddled with amyloid plaques(in orange) that clog the spaces between nerve cells.
Volume 88, Issue 14
BLOCKING AMYLOID
Alzheimer's researchers will soon know whether blocking amyloid-β can slow down the debilitating disease
COVER: The brains of people with Alzheimer's disease are riddled with amyloid plaques(in orange) that clog the spaces between nerve cells.
Credit: Elan Pharmaceuticals
» Full Article
April 5, 2010 Issue
Volume 88, Issue 14
April 5, 2010 Issue, Vol. 88 | Iss. 14
Alzheimer's researchers will soon know whether blocking amyloid-β can slow down the debilitating disease
(pp. 12-17)
Features
Business
Sangamo Biosciences wants genome editing technology to touch on multiple application areas (pp. 20-23)
Government & Policy
Measurement agency gets facelift with new director, more focused mission (pp. 30-32)
Cover Story: The Amyloid Question
The Dimebon Debacle
Medivation and Pfizer salvage what they can from the failure of a large Phase III trial for a promising Alzheimer's drug
Web ExclusiveNews of the Week
Survival Of The Weakest
Catalyst Discovery: Least stable intermediates can lead to the best catalysts
(p.7)EPA Targets Bisphenol A
Regulation: Agency will examine levels of plastics chemical in water supply and effects on wildlife
(p.8)Thorium Complex Almost Maxes Out
Inorganic Chemistry: 15-Coordinate thorium aminodiboranate sets a record, just one bond short of a perfect 16
(p.8)Gene Patents Ruled Invalid
Biotechnology: Industry says setback will not undermine multi-billion-dollar business
(p.9)Countering Sleeping Sickness
Drug Development: New compounds cure mice of early-stage infections
(p.10)Earth-Friendly Chlorine
Technology: Bayer’s new cathode saves energy, reduces greenhouse gas emissions
(p.10)Talking About Geoengineering
Climate Intervention: California conference calls for research that is responsible and open
(p.11)Departments
Business
Sangamo Biosciences wants genome editing technology to touch on multiple application areas
(pp. 20-23)
After two big departures, business is good for remaining players
(pp. 24-26)
ACS Meeting News: Using chemistry tools to refine an Alzheimer's drug candidate
(p.14)
Eastward Expansion: Plans call for doubling cellulosic capacity in China
(p.18)Concentrates
(pp. 18-19)
(pp. 18-19)- DSM Selling Agro, Melamine Units
- Lenzing Ups Fiber Capacity Again
- Hexion To Make Vinyl Esters In China
- Celanese, SABIC Plan Polyacetals
- Styron Appoints Pappas To Top Post
- Thermo, Lilly In Supply-Chain Deal
- Lyondell To Pay For Site Cleanup
- BASF, NOD Apiary Help Bees Survive
- Pfizer And Teva Tussle Over Viagra
- Boehringer Launches Venture Capital Fund
- GSK Signs Up For Isis Technology
- Companies Ink siRNA Deals
- Business Roundup
Government & Policy
Measurement agency gets facelift with new director, more focused mission
(pp. 30-32)
Renowned scientist recognized for his public service in science and technology
(p.29)
Science & Technology
Medivation and Pfizer salvage what they can from the failure of a large Phase III trial for a promising Alzheimer's drug
Web Exclusive
Alzheimer's researchers will soon know whether blocking amyloid-β can slow down the debilitating disease
(pp. 12-17)
ACS Meeting News: Analytical chemists devise methods to confirm foods are what they claim to be
(pp. 36-37)
ACS Meeting News: Increasing computational power makes possible simulations of geology's nitty-gritty chemistry
(pp. 39-40)Newscripts
Editor's Page
This guest editorial is by Ted Kaufman, Democratic senator from Delaware.
(p.3)