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Copyright © 2012 American Chemical Society
September 3, 2012 Cover
Volume 90, Issue 36
COVER: Some 3 million people in India have tuberculosis, according to the World Health Organization. Photo of X-ray and patient taken in Chennai, India.
Volume 90, Issue 36
Increasingly discouraged by genomics-based discovery, researchers revert to whole-cell screening for tuberculosis treatments
COVER: Some 3 million people in India have tuberculosis, according to the World Health Organization. Photo of X-ray and patient taken in Chennai, India.
Credit: Atul Loke/TB Alliance
» Full Article
September 3, 2012 Issue
Volume 90, Issue 36
September 3, 2012 Issue, Vol. 90 | Iss. 36
Increasingly discouraged by genomics-based discovery, researchers revert to whole-cell screening for tuberculosis treatments
(pp. 15-24)
Features
Government & Policy
FDA struggles to identify products, optimize review process (pp. 46-48)
Science & Technology
ACS Meeting News: Massive marine supply of metal drives researchers to design selective, durable sorbents (pp. 60-63)
A Nonprofit Network For Tuberculosis Drugs
Developing a drug for a neglected disease economically involves wide-reaching partnerships
(pp. 26-27)News of the Week
Membrane Separates Oil And Water With Ease
Materials: Hydrophilic-oleophobic combo could clean up oil spills
(p.9)Costly Setbacks For Big Pharma
Pharmaceuticals: Bristol-Myers Squibb, Eli Lilly & Co. halt work on drug candidates
(p.10)Victory For Stem Cell Research
Policy: Court affirms legality of federally funded research on human embryonic stem cells
(p.10)Arctic Ice Record Low
As of late August, the ice in the Arctic covers the least area it has in three decades
(p.11)Demystifying Ocean Methane
Chemical Oceanography: Microbes that make methylphosphonate constitute a new biosynthetic pathway
(p.11)Chemists Gather In Prague
International: European Association for Chemical & Molecular Sciences holds fourth biennial conference
(p.12)Romney To Focus On Fossil Fuels
Energy Policy: Plan would end subsidies for renewable energy, makes no mention of climate change
(p.12)DuPont To Divest Automotive Coatings
Planned sale to private equity firm follows acquisitions in biobased materials
(p.13)Wiring Up Living Tissue
Sensing: Merging biology and electronics could lead to smart implants and prosthetics
(p.13)Departments
Business
Repurposed labs to work on drug discovery and metabolic testing
(pp. 40-43)
Making transgenic animals to produce drugs has matured, but few products have come to market
(pp. 34-38)
Fee-for-service contracting rises in an opportunistic approach to drug discovery research
(pp. 30-33)
Increasingly discouraged by genomics-based discovery, researchers revert to whole-cell screening for tuberculosis treatments
(pp. 15-24)
Developing a drug for a neglected disease economically involves wide-reaching partnerships
(pp. 26-27)Concentrates
(pp. 28-29)
(pp. 28-29)- Private Equity Bids For TPC
- Germany’s Q-Cells Going To Hanwha
- Sapphire Reports Big Algae Harvest
- BASF Ups Global Glycol Capacity
- PDVSA Investigates Venezuelan Blast
- Airbus, Aemetis Plan Jet Fuel From Oils
- Trash-To-Sugar Process Explored
- Tessenderlo Takes Strategic Actions
- DuPont Insecticides Going To Syngenta
- Monsanto And Alnylam Join For Agriculture
- Hospira Will Acquire Indian API Facility
- Aesica Teams Up With Bradford University
- Former Roche Exec To Lead AstraZeneca
- Business Roundup
Government & Policy
Scientists oppose financial disclosure requirements of insider-trading ban
(pp. 50-54)
Office of Personnel Management asks federal scientists, engineers to volunteer
(p.56)
FDA struggles to identify products, optimize review process
(pp. 46-48)Education
Workshop for starting chemistry faculty focuses on developing teaching skills
(p.76)
Instructors aim to make science more relevant for undergrads not majoring in the subject
(pp. 74-75)
Science & Technology
ACS Meeting News: University of Pennsylvania chemist fostered electrochemistry, ACS, and chemical history
(pp. 72-73)
ACS Meeting News: Chemists discuss the growing role of natural products in developing new pesticides
(pp. 64-67)
ACS Meeting News: With new methods to modify protein backbones, chemists probe what makes proteins stable
(pp. 68-71)
ACS Meeting News: Massive marine supply of metal drives researchers to design selective, durable sorbents
(pp. 60-63)Concentrates(pp. 58-59)
(pp. 58-59)- New Phosphinidene Transfer Reagents
- New Chemically Modified Single-Stranded RNA Turns On RNAi Pathway
- Biomimetic And Extreme Surface-Area Frameworks
- Coating Helps Nanoparticles Penetrate Brain Tissue
- Reaction Yields Flat Hydrogen-Coated Surfaces
- Method Detects Zeptomoles Of TNT
- Droplets From Mold May Seed Rain Forest Aerosols
- Urban Soot Particles May Warm Climate Less Than Believed
Career & Employment
Tips for scientists preparing a talk about their work
(p.80)Newscripts
Editor's Page
Letters
Letters(pp. 6-7)
(pp. 6-7)
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