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Biological Chemistry

Noninvasive Medical Techniques

March 12, 2012 | A version of this story appeared in Volume 90, Issue 11

Feb. 13, page 26: Quest Diagnostics says its Stratify JCV test kits will be available in the second quarter of 2012, not next year.

I found Aaron Rowe’s article on noninvasive optical medical diagnosis techniques interesting (C&EN, Jan. 2, page 25). However, I was surprised that there was no mention of two commonly used existing techniques: pulse oximetry and transcutaneous bilirubinometry. The former is something most of us are familiar with, utilizing red and infrared light to measure blood oxygen levels through a fingertip. The latter measures skin bilirubin levels using multiple-wavelength light-emitting diodes, then correlates the result to the total serum bilirubin levels in preterm infants with neonatal jaundice.

Recently, I was happy to see both techniques being used in the treatment of my premature child (along with phototherapy for the jaundice). More than a matter of convenience or pain avoidance, these techniques are important when the patient’s blood supply is limited or susceptible to infection.

By Dave VanderWiel
Brecksville, Ohio

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