Issue Date: January 16, 2017
Sweeter hookups between sugars using a macrocyclic catalyst
Assembling oligosaccharides and polysaccharides can be tricky business. The steric and electronic elements that come into play when hooking one sugar onto another makes the synthesis of these molecules unpredictable. Now, inspired by the enzymes that connect sugars to one another in cells, Eric N. Jacobsen and coworkers at Harvard University have developed a macrocyclic catalyst that predictably and reliably builds certain types of sugar linkages—known as β-glycosidic bonds—in a stereospecific manner . . .
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- Chemical & Engineering News
- ISSN 0009-2347
- Copyright © American Chemical Society