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C&EN congratulates Dan Fagin on winning the 2014 Pulitzer Prize in General Nonfiction for “Toms River: A Story of Science and Salvation” (Bantam Books). C&EN’s Rudy Baum reviewed “Toms River” last May.
Copyright © 2008 American Chemical Society
September 1, 2008 Cover
Volume 86, Issue 35
COVER: Cystic fibrosis, which affects the lungs, is caused by a faulty membrane channel protein, the cystic fibrosis transmembrane conductance regulator (whose structure is shown here), which balances chloride ions inside and outside cells.
Volume 86, Issue 35
CLEARING CHANNELS
Cystic fibrosis patients could soon benefit from breakthrough small-molecule drugs that treat their underlying disease instead of just their symptoms
COVER: Cystic fibrosis, which affects the lungs, is caused by a faulty membrane channel protein, the cystic fibrosis transmembrane conductance regulator (whose structure is shown here), which balances chloride ions inside and outside cells.
Credit: Epix Pharmaceuticals
» Full Article
September 1, 2008 Issue
Volume 86, Issue 35
September 1, 2008 Issue, Vol. 86 | Iss. 35
Cystic fibrosis patients could soon benefit from breakthrough small-molecule drugs that treat their underlying disease instead of just their symptoms
(pp. 15-23)
Features
Government & Policy
Department of Defense memo may reverse the recent rise in government restrictions on some university research (pp. 38-40)
Science & Technology
Highlights include algae biofuel factories, hunting neutrinos, and more (pp. 45-48)
News of the Week
Chemists Receive Top Awards
ACS members are among recipients of national medals of science, technology
(p.10)Growth Amid Pharma Cutbacks
Biotech firm Gilead adds jobs, while UCB and Abbott cut back
(p.10)Challenging EPA
States will sue to force agency to regulate oil refinery emissions
(p.11)Two-Faced Flowers
Tobacco plants add nicotine to their nectar to improve cross-pollination
(p.11)O2 Requirement For Burning Rises
Experiments suggest Mesozoic oxygen levels were higher than previously expected
(p.12)Breaking C–F Bonds
Reaction could lead to ways to dispose of or recycle fluorocarbons
(p.13)CO2 As Feedstock
Mitsui will make methanol from the greenhouse gas
(p.13)Departments
Business
Top executives are charged with streamlining an R&D behemoth as they build a biopharma juggernaut
(pp. 27-30)
Germany's chemical industry association revels in the good times and is working to keep them going
(pp. 31-34)
Transformed by new managers, fine chemicals producer New Chemphy attracts big-name customers
(p.35)
The government has issued clear warnings about what might lie ahead, and the chemical industry is taking steps to respond
(p.36)Concentrates
(pp. 25-26)
(pp. 25-26)- King Seeks To Buy Alpharma
- Chemical Explosion Kills 20 In China
- Ferro Acquires BP Intermediate
- Agricultural Firms Investigate Corn Stover
- Glaxo Signs Deal For Epilepsy Drug
- Codexis Expands Its Partnership With Arch
- BASF Launches BioBased Polyol ...
- ... As Dow Debuts Biobased Antifreeze
- Solutia Aids Solar Power Plant
- Genzyme And Advinus Target Malaria Drugs
- DSM Invests In Ingredients Firm ...
- ... But Closes Chinese Citric Acid Plant
- Dow Forms Water Pact With Universities
- Business Roundup
ACS News
This time, society officials and journal editors go to china's national meeting
(pp. 66-67)
Government & Policy
Department of Defense memo may reverse the recent rise in government restrictions on some university research
(pp. 38-40)
Chemical safety board finds a powerful, popular tool in animated videos of chemical plant accidents
(pp. 41-42)
Science & Technology
Cystic fibrosis patients could soon benefit from breakthrough small-molecule drugs that treat their underlying disease instead of just their symptoms
(pp. 15-23)
Highlights include algae biofuel factories, hunting neutrinos, and more
(pp. 45-48)
Analytical chemists piece together the origin and fate of environmental contaminants
(pp. 49-52)
Structures support previously suspected pathway for making carbon-fluorine bonds
(pp. 53-56)
Largest ever ocean chemistry study will span about 20 years
(pp. 57-60)
Hydrothermal vents could be a significant source of dissolved iron in the South Pacific
(pp. 62-63)Newscripts
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