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Copyright © 2011 American Chemical Society
March 14, 2011 Cover
Volume 89, Issue 11
COVER: Artist's rendition of a G-protein-coupled receptor made from a hodgepodge of pills.
Volume 89, Issue 11
TRASMEMBRANE PRTEINS
Debut of G-protein-coupled receptors will bolster drugmakers’ tool kits
COVER: Artist's rendition of a G-protein-coupled receptor made from a hodgepodge of pills.
Credit: Shutterstock/C&EN
» Full Article
March 14, 2011 Issue
Volume 89, Issue 11
March 14, 2011 Issue, Vol. 89 | Iss. 11
Debut of G-protein-coupled receptors will bolster drugmakers’ tool kits
(pp. 15-21)
Features
Science & Technology
When it goes awry, this defense mechanism can contribute to all stages of cancer progression (pp. 40-43)
ACS News
Chemistry and chemical engineering graduates in 2009 faced a tough job market and falling median salaries (pp. 49-53)
News of the Week
House Panel Votes To Halt Climate Rules
Environment: Republicans push antiregulatory agenda
(p.9)China Outlines Path Forward
People’s Congress: Business leaders see opportunity in country’s next five-year plan
(p.10)Nanodiamonds Fight Cancer
Chemotherapy: Faceted nanomaterials deliver drugs to tumor cells
(p.10)Oil Spill’s Air Effects Probed
Deepwater Horizon: Aircraft data show how accident’s emissions affected Gulf of Mexico atmosphere
(p.11)Poised To React
Nanoscience: Tethering molecules to gold surface forces reaction
(p.12)Senate Rejects House Budget Cuts
Congress: Legislators remain divided about how much to reduce fiscal 2011 spending
(p.12)First Hit For A Cancer Target
Drug Discovery: Academic collaboration leads to nanomolar inhibitor for phosphatase methylesterase-1
(p.13)Departments
Business
After restructuring, CEO Feike Sijbesma has a four-pronged strategy for expansion
(pp. 24-27)
Cellular Dynamics, a pioneer in induced pluripotent stem cells, is creating a new services sector
(pp. 28-29)Concentrates
(pp. 22-23)
(pp. 22-23)- Major Kuwait-China Venture Takes Shape
- Oxea Will Boost Carboxylic Acids
- Albemarle Expanding Bromine Venture
- BASF And Evolva Join For Synthetic Biology
- Solvay hiking Polymer Capacity
- BASF Again Mulls Brazilian Acrylics
- GSK Ends Pact With Targacept
- Cadila, Holtzman Invest In Rwanda
- Neste Completes Diesel Plant
- BMS And WuXi Team Up For Testing
- Renovo Slashes Jobs After Trial Failure
- Eisai Realigns U.S. Operations
- Business Roundup
ACS News
A Brief comparison of chemical engineering and chemistry grads
(p.52)
Chemistry and chemical engineering graduates in 2009 faced a tough job market and falling median salaries
(pp. 49-53)
Election of candidates will be main order of business at ACS National meeting in Anaheim, Calif.
(pp. 54-55)
Government & Policy
Key Republican Party leaders back Clean Energy R&D program
(pp. 32-33)
Regulators join forces with developers to speed up approval of transformative devices
(pp. 34-35)
U.S. federal agencies examine their role in capacity building in developing countries
(p.36)
Science & Technology
Debut of G-protein-coupled receptors will bolster drugmakers’ tool kits
(pp. 15-21)
Chiral Catalysis: Nanoscale proximity of reactants enhances asymmetric hydrogenation
(p.39)
When it goes awry, this defense mechanism can contribute to all stages of cancer progression
(pp. 40-43)
As they transfer to higher organisms in a food web, nanomaterials can increase in concentration, new studies show
(pp. 44-46)Concentrates(pp. 38-39)
(pp. 38-39)- Fluoride Blocks Enzyme Site
- Study Suggests New Criteria For Electrocatalysts
- Rhodium-Catalyzed Reaction Pinned Down
- Mycobacteria Have A System For Acquiring Iron From Heme …
- … And Can Now Enter The Spotlight For In-Cell Detection
- Laser-Induced Shock Wave Chromatography
- Forster Reaction Delivers Generic Drug
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