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Copyright © 2008 American Chemical Society
April 14, 2008 Cover
Volume 86, Issue 15
COVER: As bacteria evolve and resist current antibiotics(like Cubist�s daptomycin, shown), drug developers strive tobring new revenue generators to market.
Volume 86, Issue 15
THE ANTIBIOTIC CHALLENGE
With short lives and uncertain profits, antibiotics are a unique development challenge for drug companies
COVER: As bacteria evolve and resist current antibiotics(like Cubist�s daptomycin, shown), drug developers strive tobring new revenue generators to market.
Credit: imagezoo
» Full Article
April 14, 2008 Issue
Volume 86, Issue 15
April 14, 2008 Issue, Vol. 86 | Iss. 15
With short lives and uncertain profits, antibiotics are a unique development challenge for drug companies
(pp. 15-20)
Features
Government & Policy
House committee probe of industry bias in agency review reaches former ACS president (pp. 35-36)
Science & Technology
Microbial meteorologists investigate how airborne microbes might influence weather (pp. 40-42)
Cover Story: An Uphill Battle
Imminent Threat
As gram-negative bacteria become resistant to current antibiotics, the search for new drugs accelerates
(pp. 21-24)The Ketek Effect
Biotechs worry that FDA has gotten tougher on approving new antibiotics
Web ExclusiveNews of the Week
Grace Reaches Asbestos Deal
Settlement could allow firm to emerge from bankruptcy by year's end
(p.11)Courting Japan
Foreign suppliers of pharmaceutical chemicals affirm commitment to country's market
(p.13)Departments
Business
Two years after a management buyout, CEO John Gaither steers old-line firm in a global expansion
(pp. 30-31)
Although they have much to worry about, petrochemical makers remain optimistic
(p.32)
As gram-negative bacteria become resistant to current antibiotics, the search for new drugs accelerates
(pp. 21-24)
Biotechs worry that FDA has gotten tougher on approving new antibiotics
Web Exclusive
With short lives and uncertain profits, antibiotics are a unique development challenge for drug companies
(pp. 15-20)Concentrates
(pp. 33-34)
(pp. 33-34)- European Drugmakers Look East For actives
- Jubilant Will Acquire Contract Firm Draxis
- Lonza Will Boost Niacin Capacity
- Rohm And Haas Buys, Sells In Electronics
- Chlorine Leak Settlement Reached
- Another Expansion Set For Abu Dhabi
- DuPont Opens Storm Shelter Test Facility
- Evonik Names Head For North America
- Praxair Oxygen Will Treat Drinking Water For The Olympics
- Nektar Ends Inhaled Insulin Programs
- Harvard And Merck Form Research Pact
- Biotech Companies Plan Job Reductions
- Business Roundup
Government & Policy
House committee probe of industry bias in agency review reaches former ACS president
(pp. 35-36)
Economic slowdown, job dip, and changing world economy should bring critical analysis of the outlook for the domestic workforce
(p.37)
Science & Technology
Microbial meteorologists investigate how airborne microbes might influence weather
(pp. 40-42)
The science that gives clothing a soft feel and fresh scent as it prevents static cling
(p.47)Career & Employment
Recent B.S. and M.S.graduates ignite their passion for chemistry within diverse businesses
(pp. 55-59)