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Copyright © 2010 American Chemical Society
March 15, 2010 Cover
Volume 88, Issue 11
COVER: istock/C&EN
Volume 88, Issue 11
PHARAMACEUTICAL OUTSOURCING
Relationships between drug companies and chemistry outsourcing partners can span years, even decades
COVER: istock/C&EN
Credit: istock/C&EN
» Full Article
March 15, 2010 Issue
Volume 88, Issue 11
March 15, 2010 Issue, Vol. 88 | Iss. 11
Relationships between drug companies and chemistry outsourcing partners can span years, even decades
(p.15)
Features
Business
North American producers are bracing for long-anticipated capacity to come on-line in the Middle East and Asia (pp. 30-33)
Cover Story: Pharma Outsourcing
Patently Right Process Chemistry
Case Study #1: Cytokinetics turns to Irix for help with a tough synthesis
(pp. 16-19)Loyal Steward Of A Small Molecule
Case Study #2: For over 25 years, Regis has
supplied 4-aminopyridine to successive
stakeholders for a new multiple sclerosis drug
(pp. 21-23)More Than A Supplier
Case Study #3: BioVectra seeks greater returns by partnering with Taxolog and Sandoz on a generic cancer drug
(pp. 25-27)News of the Week
Unraveling Thalidomide's Tragic Effects
Cell Biology: Researchers discover a protein involved in causing birth defects related to the drug
(p.9)Chemistry Over Colorado
Chlorine Surprise: Reactions may process up to one-fifth of inland nitrogen oxide emissions
(p.10)European Chemicals Agency Proposes Expanded Regulations
Chemical Controls: Trichloroethylene and seven other compounds targeted
(p.11)New Chains For Ionic Liquids
Molecular Design: Kinked fatty acid side chains create a new class of low-melting-point salts
(p.11)Exelixis Restructures
Biotech: Cancer drug firm shifts resources to development and cuts 40% of jobs
(p.12)Abbott Takes On Facet
Big pharma firm wins bid for a promising pipeline of multiple sclerosis, oncology drugs
(p.13)Climate-Change Panel Under Scrutiny
Inquiry: Science academies will assess UN's prestigious body
(p.13)Departments
Business
North American producers are bracing for long-anticipated capacity to come on-line in the Middle East and Asia
(pp. 30-33)
Biotech hub in Paris that keeps a science legacy alive now needs to expand
(pp. 35-36)
Cipla gears up for commercial production, joining other local players
(pp. 38-39)
Case Study #1: Cytokinetics turns to Irix for help with a tough synthesis
(pp. 16-19)
Case Study #2: For over 25 years, Regis has
supplied 4-aminopyridine to successive
stakeholders for a new multiple sclerosis drug
(pp. 21-23)
Case Study #3: BioVectra seeks greater returns by partnering with Taxolog and Sandoz on a generic cancer drug
(pp. 25-27)
Relationships between drug companies and chemistry outsourcing partners can span years, even decades
(p.15)Concentrates
(pp. 28-29)
(pp. 28-29)- LyondellBasell Formally Rejects Reliance Offer
- CF's Sweetened Offer Tempts Terra
- Lanxess Expands Rubber Capacity
- Lanxess Completes Power Plant In Brazil
- Afton Chemical Buys Polartech
- Bruker To get Three Varian Businesses
- Dow Expands Agrosciences R&D
- Instrument Makers, Universities Link
- Bayer Acquires Artificial Muscle
- Covidien Lines Up More Technetium
- Cellzome Gets Another Investment From GSK
- Big Pharma Confronts Drug Setbacks
- Wacker Boosts Its Protein Production
- Business Roundup
Government & Policy
But many in Congress are raising serious questions about the agency's human space exploration plans
(pp. 42-43)
National science board recommends ways to fend off challenges from global competitors
(pp. 44-46)
Science & Technology
Chemical Ecology: Beewolf digger wasps use bacterial antibiotics to protect the next generation
(p.54)
Heat and a magnetic field lead liquid lithium to swirl on its own, like a whirlpool
(p.48)
Enhancing the aroma of food might help dieters eat less
(pp. 51-52)Career & Employment
With biotech struggling to recover, many chemists remain out of work in California
(pp. 61-63)