Copyright © 2010 American Chemical Society
June 7, 2010 Cover
Volume 88, Issue 23
COVER: Veer
Volume 88, Issue 23
NEW DIRECTIONS IN R&D
The spending race is over in pharmaceutical R&D, with companies now focused on doing more with less
COVER: Veer
Credit: Veer
» Full Article
June 7, 2010 Issue
Volume 88, Issue 23
June 7, 2010 Issue, Vol. 88 | Iss. 23
The spending race is over in pharmaceutical R&D, with companies now focused on doing more with less
(pp. 13-18)
Features

Government & Policy
Scientists are being intimidated and harassed because of their research, they tell congress
(pp. 31-32)
Cover Story: Research Recalibrated
R&D On The Chopping Block
Big pharma's path through the recession is littered with job and program cuts and plant closures
(pp. 14-15)News of the Week
House Passes Science Bill
Legislation: Third time's the charm for the measure to bolster science research, education, and innovation
(p.9)Metabolites Turn On Pathogen's Virulence
Natural Products: Staph produces molecules that help it colonize humans
(p.10)Catalysis In Crystals
Inorganic Chemistry: Single crystals of iridium complex can exchange ligands and hydrogenate ethylene
(p.11)Downsizing Ethylene
Petrochemicals: Two Japanese firms prepare for onslaught of Middle Eastern capacity
(p.12)FDA Approval Is Not A Shield
Liability: Like brand-name companies, generic drug firms can be sued for not warning about risks
(p.12)Departments
Business
Executives have sworn off reinvention, instead focusing on what they think the company does best
(pp. 21-23)
Private equity firm forays into high-purity chemicals with former Rohm and Haas CEO Raj Gupta
(p.29)
The spending race is over in pharmaceutical R&D, with companies now focused on doing more with less
(pp. 13-18)
Big pharma's path through the recession is littered with job and program cuts and plant closures
(pp. 14-15)Concentrates
(pp. 19-20)
(pp. 19-20)- J&J Strengthens Its Respiratory Pipeline
- Dow's Credit Outlook Upgraded By Fitch
- Dow Is Selling One European Facility To Monument
- Dow Is Selling One European Facility To Japan’s Arakawa
- OCI And Cabot Hike Asian Carbon Black
- Evonik Ups Silica, Nylon Intermediate
- Borealis Opens One Plant, Plans Another
- Leukemia Group Backs Onconova Treatment
- Radiochemical Supplies Enhanced
- Grace Opens Aussie Construction Plant
- BASF Will Enter L-Menthol Market
- SEC Charges Biotech R&D Head With Lying
- Business Roundup
Government & Policy
Scientists are being intimidated and harassed because of their research, they tell congress
(pp. 31-32)
Congress, GAO point to consistent flaws in CDC units' environmental health practices
(pp. 33-34)
Environmental group draws attention to risks posed by use of toxic chemicals
(p.35)Science & Technology
Materials: Microscopy method reveals positions of catalytic metals anchored inside pores
(p.42)
Definitive solution of the structure of an enzyme in isoprenoid biosynthesis could lead to new antibiotics
(pp. 39-40)
Studies pin down key intermediates in versatile migratory alkene insertion reactions
(p.41)
Insights: Forty years of environmental protection is showing some benefits
(p.43)

