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Copyright © 2011 American Chemical Society
May 30, 2011 Cover
Volume 89, Issue 22
COVER: An identified peptide fragment, or phylomer (purple), sits within its host bacterial protein (green).
Volume 89, Issue 22
FINE CHEMICALS
Small firms develop better peptide drug candidates to expand this pharmaceutical class and attract big pharma partners
COVER: An identified peptide fragment, or phylomer (purple), sits within its host bacterial protein (green).
Credit: Phylogica
» Full Article
May 30, 2011 Issue
Volume 89, Issue 22
May 30, 2011 Issue, Vol. 89 | Iss. 22
Small firms develop better peptide drug candidates to expand this pharmaceutical class and attract big pharma partners
(pp. 13-20)
Features
Government & Policy
Recent failure of UN talks raises concerns over likelihood of success of efforts to create a green economy (pp. 39-41)
Science & Technology
More than 30 years after his death, a selection of R. B. Woodward’s notes on conducting materials is published (pp. 46-49)
Cover Story: Improving Peptides
Making Peptides At Large Scale
Efficient synthesis is helping to renew interest in the peptide drug market
(pp. 21-25)News of the Week
Ubiquitins In Four-Part Harmony
Biomacromolecular Synthesis: Tetraubiquitin is the longest protein made chemically
(p.7)Streamlining Regulation
Government: Agencies offer plans for cutting costs, paperwork for businesses
(p.8)Vertex Hepatitis Drug Is Approved
Pharmaceuticals: Stage is set for a heated competition between Vertex and Merck
(p.8)Metals Recycling Falls Short
Sustainability: Recycling rates must rise to conserve, maintain resources, UN report says
(p.9)Watery Magma From The Moon
Moon's Origin: High levels of water found in ancient lunar magma bubbles add twist to giant-impact theory
(p.10)Departments
Business
As Europe moves toward a ban on some phthalates, producers of the plasticizers look to diversify
(pp. 28-31)
Extracts and API producer makes its own drug discoveries to keep ahead of competitors
(pp. 32-34)
Elastomer producers set up shop in Singapore and Thailand
(pp. 35-36)Concentrates
(pp. 26-27)
(pp. 26-27)- Big Chemical Mergers On Track To Rise
- Dow Is Promoting Incineration
- Two Die At Shintech Plant In Louisiana
- DuPont Regroups To Absorb Danisco
- Hemp Chair Relies On Resin From BASF
- Chemtura Forms Bromine Alliance
- Invista Will Expand Spandex In Brazil
- Liquid Metal Battery Gets Gates Funding
- BASF Slates TDI Plant For Europe
- Idemitsu Bids For Agrochemical Firm
- Almac Toasts Its U.S. Headquarters
- Accelrys Has Another Lab Notebook Deal
- Valeant And Watson Buy Into Generics
- Business Roundup
ACS News
Government & Policy
Recent failure of UN talks raises concerns over likelihood of success of efforts to create a green economy
(pp. 39-41)
Senators question cost, lack of applications for greenhouse gas storage plans
(p.42)
Science & Technology
Efficient synthesis is helping to renew interest in the peptide drug market
(pp. 21-25)
Small firms develop better peptide drug candidates to expand this pharmaceutical class and attract big pharma partners
(pp. 13-20)
More than 30 years after his death, a selection of R. B. Woodward’s notes on conducting materials is published
(pp. 46-49)
Historical analysis of inflated yield and purity data in organic synthesis papers points to pressure to produce high-impact results
(pp. 50-52)
Scientists use various ways to strengthen immune response to carbohydrate cancer antigens
(pp. 53-57)Concentrates(pp. 44-45)
(pp. 44-45)- Sniffing Out Black- Currant Structures
- Organic Layer Smooths Dielectric Films
- Microbe’s Protein Structure Elucidated
- Pulling Out Protein Complexes
- Molecular Constraint Inhibits Peptide Aggregation
- Peptide-Nanotube Assemblies Create Superstructures
- Key Catalyst Support Parameters Identified
- Scorpion Venom Unfriendly To Fungi