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Copyright © 2012 American Chemical Society
April 16, 2012 Cover
Volume 90, Issue 16
COVER: A histone methyltransferase inhibitor interacts with the epigenetic enzyme DOT1L.
Volume 90, Issue 16
Companies make headway in understanding epigenetic targets and designing drugs to modulate them
COVER: A histone methyltransferase inhibitor interacts with the epigenetic enzyme DOT1L.
Credit: Epizyme
» Full Article
April 16, 2012 Issue
Volume 90, Issue 16
April 16, 2012 Issue, Vol. 90 | Iss. 16
Companies make headway in understanding epigenetic targets and designing drugs to modulate them
(pp. 12-19)
Features
Government & Policy
The flood of natural gas production is hoped to slow climate change, but it might just make it worse (pp. 34-37)
Science & Technology
Medicinal chemists debut five drug candidates and describe their discovery. (pp. 42-45)
Cover Story: Controlling The Code
Probing Questions
A public-private partnership aims to find and share new compounds for epigenetics research
(p.20)News of the Week
Ion Channel In Motion
Computational Biochemistry: Simulation tour de force visualizes protein’s opening and closing
(p.7)Amgen Will Buy Peptide Firm Kai
Biopharmaceuticals: Acquisition adds a late-stage therapeutic to the biotech’s pipeline
(p.8)Curbing Antibiotic Use
Health: FDA calls on drug industry to phase out nonmedical uses in animals
(p.8)Chemical Reactors On Demand
Chemical Engineering: 3-D printer produces custom vessels for chemical synthesis
(p.9)Corning Buys Lab Supplies Business
Consumables: Acquisition of Becton, Dickinson & Co. business expands life sciences unit
(p.9)Chemical Safety Board’s Right To Probe Gulf Oil Rig Accident Questioned
Safety: Transocean accused of preventing progress of investigation
(p.10)Nanoparticle Arrays For Faster Electronics
Materials Science: First uniform arrays of topological insulators grown
(p.10)Departments
Business
A public-private partnership aims to find and share new compounds for epigenetics research
(p.20)
Rural China area’s intense pollution abates as local manufacturer reduces, treats its wastewater
(pp. 31-32)
Optimism about the economy, chemical outlook reigned at the IHS Chemical conference
(pp. 29-30)
Government-backed venture funds target emerging firms to modernize health care
(pp. 24-28)
Companies make headway in understanding epigenetic targets and designing drugs to modulate them
(pp. 12-19)Concentrates
(pp. 22-23)
(pp. 22-23)- Cleantech Investment Falls
- Cytec To Buy Umeco In Composites Push ...
- ... As Dow, Ford Join For Composites
- BASF Picks India For Specialties Plant
- Companies Set Large Aromatics Expansion
- PPG Will Cut 2,000 Coatings Jobs
- Huntsman Will Expand Ethylene Oxide Plant
- Elevance And XiMo Advance Metathesis
- Merck Signs On To Early-Stage Fund
- Kyocera And Partners Plan Solar Facility
- Shimadzu Opens Lab Center In Texas
- Evans Acquires Testing Firm PTRL
- URL Brings Gout Drug To Takeda
- Business Roundup
Government & Policy
Personal care products industry supports overhaul of decades-old safety law
(p.38)
The flood of natural gas production is hoped to slow climate change, but it might just make it worse
(pp. 34-37)
Science & Technology
Porous metal organic framework compound selectively binds ethylene and other lightweight feedstocks
(p.46)
Medicinal chemists debut five drug candidates and describe their discovery.
(pp. 42-45)Concentrates(pp. 40-41)
(pp. 40-41)Career & Employment
Scientists transition into entrepreneurship by taking risks and following their passions
(pp. 50-52)Newscripts
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