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Copyright © 2012 American Chemical Society
July 23, 2012 Cover
Volume 90, Issue 30
COVER: In some patients with non-small-cell lung cancer, physical rearrangements in the ALK gene result in a mutated form of the corresponding protein, the activity of which can be inhibited by Pfizer’s drug Xalkori. Using a companion diagnostic developed by Abbott Laboratories, physicians identify patients who have the mutation.
Volume 90, Issue 30
Companion diagnostics matching patients with drugs are becoming mainstream
COVER: In some patients with non-small-cell lung cancer, physical rearrangements in the ALK gene result in a mutated form of the corresponding protein, the activity of which can be inhibited by Pfizer’s drug Xalkori. Using a companion diagnostic developed by Abbott Laboratories, physicians identify patients who have the mutation.
Credit: Pfizer
» Full Article
July 23, 2012 Issue
Volume 90, Issue 30
July 23, 2012 Issue, Vol. 90 | Iss. 30
Companion diagnostics matching patients with drugs are becoming mainstream
(pp. 10-13)
Features
Business
Chemists who lost their jobs after the closure of Pfizer’s Sandwich site are creating their own companies (pp. 16-18)
Government & Policy
Opponents contend that revised building rating system would target chemicals in construction materials (pp. 26-27)
News of the Week
Peter J. Stang Named Priestley Medalist
ACS Awards: Supramolecular chemistry pioneer is also recognized for leading ACS journals
(p.5)Instrumentation Companies Continue Push Into Clinical Diagnostics
Instrumentation: Thermo Fisher, Life Technologies acquire clinical diagnostics firms
(p.6)Unemployment Data For Chemists Improve Slightly
ACS News: Unemployment rate of 4.2% for ACS members in 2012 is down from 4.6% level in 2011
(p.6)Flame Retardants In Furniture Foam Are Not Effective, CPSC And UL Officials Tell Senate Subcommittee
Safety groups say the chemical mixtures offer little protection
(p.7)Human Genome Sciences Accepts Offer From GSK
Bid was raised to $3.6 billion after initial rejection
(p.7)How Nanosilver Zaps Germs
Antimicrobials: Ions, not nanoparticles, are the killers
(p.8)Slate Set For American Chemical Society's Fall Election Ballot
Candidates for president-elect and directors are named
(p.8)Europe Opens Up
EC and U.K. release open-access policies one day apart and encourage the rest of Europe to follow suit
(p.9)Nanohoops Scaled Up 100-fold
Organic Chemistry: Grams of benzene-based rings could aid synthesis of conductive nanowires
(p.9)Departments
Business
As Chinese labs get more sophisticated, the need for support grows
(p.22)
Backed by a big new owner in the U.S., firm seeks aggressive growth
(pp. 20-21)
Chemists who lost their jobs after the closure of Pfizer’s Sandwich site are creating their own companies
(pp. 16-18)Concentrates
(pp. 14-15)
(pp. 14-15)- Georgia Gulf Will Merge With PPG Chemicals Unit
- Olin To Acquire K.A. Steel Chemicals
- BASF Targets Battery Materials Sales Boost
- Teijin Will Expand Japanese DMT Plant
- Codexis Rejiggers Its Deal With Shell
- Afton Plans Additives Facility For Singapore
- Trygg Pharma Buys U.K. Factory
- Solvay Opens Polymer Facility In China
- FDA Approves Drugs For HIV And Obesity
- TPG Will Acquire Par Pharmaceutical
- Verastem Has Deals With Pfizer, Eisai
- MedImmune To Close Two California Sites
- Biogen And Partners Tackle ALS R&D
- Business Roundup
- All Concentrates
ACS News
Society issues call for abstracts
(p.40)
Elections: Candidates for president-elect and directors are named
Society honors 96 members for their contributions to science and the profession
(pp. 36-37)
Government & Policy
Opponents contend that revised building rating system would target chemicals in construction materials
(pp. 26-27)
CSB discusses Bayer CropScience accident in call for safer practices
(p.28)Books
A personal perspective from a half-century career of research in the noble gases
(pp. 34-35)
Science & Technology
Fundamental studies and coating strategies help avoid detrimental buildup
(pp. 31-32)
The first woman in the Royal Society of Chemistry’s presidential post compares diversity in science in the U.S. and U.K.
(p.33)
Companion diagnostics matching patients with drugs are becoming mainstream
(pp. 10-13)
Antimicrobials: Ions, not nanoparticles, are the killers
Organic Chemistry: Grams of benzene-based rings could aid synthesis of conductive nanowires
Concentrates(pp. 29-30)
(pp. 29-30)- Building A Bigger Borazine
- Diacetyl Exacerbates Amyloid Toxicity
- Sprinklers Reduce Arsenic In Rice
- Strong Paramagnetism Makes Strong Bonds
- Carbon Dots Created From Orange Juice
- New Details On Water Hexamer Structures
- Geologic Sulfur Cycle Reexamined
- Binding Study Could Aid Search For Better Selectin Blockers
Career & Employment
Chemists are discovering engaging jobs that allow them to influence patient health
(pp. 41-43)Newscripts
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