Already have an ACS ID? Log in
Renew your membership, and continue to enjoy these benefits.
Already an ACS Member? Log in here
Choose the membership that is right for you. Discounts will be applied automatically at checkout.
Enjoy these benefits no matter which membership you pick.
Most Popular in Analytical Chemistry
While synthesizing fluorescent dyes like these, Jon Grimm of Janelia Research Campus often has to mask or “protect” parts of his molecules with functional groups that are less reactive. This step allows him to modify one part of the dye molecule without undoing the work he did on another. The protected versions of the molecules are colorless. But when Grimm adds sodium hydroxide or tetra-n-butylammonium fluoride (TBAF) to the protected molecules, they lose their protecting groups, revealing their colors and fluorescing under ultraviolet light. Grimm works with Janelia’s chief toolmaker Luke Lavis and shares the dyes they make with the biochemists on campus and around the world for use in high-resolution biological imaging.
Do science. Take pictures. Win money. Enter our photo contest here.
Related C&EN Content:
This article has been sent to the following recipient: