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Microscopy

Chemistry In Pictures

Chemistry in Pictures: The inner life of cells

by Manny Morone
January 6, 2020
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Most Popular in Analytical Chemistry

Four bovine cells stained red, green, and blue seen under a microscope.
Credit: Ralph Lange

Ralph Lange used a confocal microscope to capture this image of bovine endothelial cells which are about 100 µm wide. Although this was just a practice exercise with dead cells, Lange’s postdoc work at Stanford University has to do with making polymer materials that can sneak RNA into cells while they’re still alive. By using a variety of stains and a microscope, Lange and coworkers can track whether the RNA has entered certain cells in real time. The fluorescent stains in this photo are Texas Red-X (red) which is binding to actin filaments; boron-dipyrromethene (blue, also known as BODIPY) binding to microtubules; and 4′,6-diamidino-2-phenylindole (green, also known as DAPI) binding to DNA in the cells’ nuclei.

Submitted by Ralph Lange

Do science. Take pictures. Win money. Enter our photo contest here.

Related C&EN Content:

CRISPR’s breakthrough problem

Chemistry in Pictures: Jingle cells

Chemistry in Pictures: Happy little plant cells.

Chemical & Engineering News
ISSN 0009-2347
Copyright © 2025 American Chemical Society

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