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Pharmaceuticals

ImmunoGen to develop route for Genentech

May 15, 2006 | A version of this story appeared in Volume 84, Issue 20
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ImmunoGen will work with Genentech to create a commercial manufacturing process for Genentech's trastuzumab-DM1, a cancer treatment based on ImmunoGen's tumor-activated prodrug (TAP) technology. The agreement increases to $44 million the amount that ImmunoGen can earn under an existing pact with Genentech. In a TAP compound, a tumor-targeting antibody is linked to a cytotoxic small-molecule agent. ImmunoGen says it has manufactured numerous TAP compounds at its Norwood, Mass., facility.

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