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Business

Pfizer licenses TransTech drugs

September 25, 2006 | A version of this story appeared in Volume 84, Issue 39
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Pfizer has signed a licensing agreement with TransTech Pharma for small- and large-molecule compounds under development by TransTech for the treatment of Alzheimer's disease. The compounds target the receptor for advancing glycation end products (RAGE). The most advanced are TTP488, an orally available small-molecule candidate that is in Phase II clinical trials, and TTP4000, a large molecule expected to begin Phase I trials this year. Under the agreement, Pfizer gains exclusive rights to TransTech's RAGE modulator portfolio. TransTech will receive up-front and near-term milestone payments totaling $155 million and could earn additional unspecified milestone and royalty payments.

Chemical & Engineering News
ISSN 0009-2347
Copyright © 2024 American Chemical Society

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