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Avecia's OligoMedicines business is expanding production of short interfering RNAs (siRNAs) at its Milford, Mass., facility. When completed by Sept. 1, the upgrade will, at the least, double capacity to 300-400 g per batch size in three areas: cleavage and deprotection, duplexation and conjugation, and chromatography. Avecia says the expansion will allow it to better address growing markets for siRNA- and aptamer-based therapeutics.
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