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Pharmaceuticals

Abbott, Genentech Form Cancer Pact

July 2, 2007 | A version of this story appeared in Volume 85, Issue 27
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Abbott Laboratories and Genentech have formed a collaboration for the research, development, and commercialization of two of Abbott's investigational cancer compounds, known as ABT-263 and ABT-869. The small-molecule compounds, discovered by Abbott scientists, are being described as targeted therapies that promise unique approaches to treating cancer. ABT-263 is a Bcl-2 family protein antagonist that restores apoptosis, or cell death, in cancer cells. ABT-869 is a kinase inhibitor that stops tumors from growing by preventing the growth of blood vessels that supply them.

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