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Web Date: February 28, 2007

Wide-Range Fluorescent pH Sensor

Molecular device emulates glass pH electrode
Department: Science & Technology
News Channels: JACS In C&EN

A new molecular sensor that matches the pH range of glass pH electrodes could be used for measuring pH in biological cells and microfluidic devices (J. Am. Chem. Soc., DOI: 10.1021/ja0686514).

The sensor, designed by A. Prasanna de Silva at Queen's University, Belfast, Northern Ireland, and coworkers, consists of four disubstituted anthracenes that fluoresce in parallel over different pH ranges by a mechanism of photoinduced electron transfer. The anthracenes have a fluorophore-spacer-receptor design . . .

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