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PTC Will Work With Roche And Celgene

by Michael McCoy
September 7, 2009 | A version of this story appeared in Volume 87, Issue 36

PTC Therapeutics has signed a research and licensing agreement with Roche for the development of small molecules with PTC’s Gene Expression Modulation by Small-Molecules, or GEMS, technology. Roche will pay PTC $12 million up front and could pay up to $239 million for each of four central nervous system disease targets if milestones are met. Separately, PTC will apply the GEMS technology to a Celgene oncology drug target. Celgene acquired an option for the research when it invested $20 million in PTC in 2007.

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