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Cellzome has formed a drug discovery alliance with GlaxoSmithKline involving epigenetics related to inflammatory disease. Under the deal, Cellzome will receive $45 million up front and could reap more than $650 million in milestone payments. GSK will get access to Episphere, Cellzome’s chemical proteomics technology for the discovery of small-molecule drugs directed at targets involved in epigenetic regulation. Cellzome received $22 million from GSK in September 2008 in a deal involving kinase-targeted therapeutics.
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