Volume 89 Issue 19 | p. 39 | Concentrates
Issue Date: May 9, 2011

Dendrimer Treats Joint Inflammation

Highly branched polymer relieves rheumatoid arthritis symptoms in mice
Department: Science & Technology
Keywords: rheumatoid arthritis, dendrimers, monocytes, inflammation

For sufferers of rheumatoid arthritis—the chronic inflammatory disease that induces pain, swelling, and eventual deformity in the joints of about 1% of the world’s population—more effective treatment could be on the way. Current medicines for the crippling disease typically target a signaling protein in the inflammatory pathway but don’t prevent eventual erosion of the bones in patients’ joints. Now, a research team led by Jean-Luc Davignon and Rémy Poupot of France’s National Institute . . .

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