Volume 89 Issue 20 | p. 36
Issue Date: May 16, 2011

A Giant Leap For Cell Analysis

Mass cytometry boosts the number of single-cell parameters that can be measured simultaneously
Department: Science & Technology
News Channels: Analytical SCENE, JACS In C&EN
Keywords: cytometry, cells, mass spectrometry, lanthanides, immunology

A novel approach is expanding the versatility of flow cytometry, a particle counting and sorting technique that has been a workhorse of biology labs for ­decades.

In flow cytometry, researchers use fluorescently labeled antibodies to distinguish among different types of cells. But the need for distinct fluorescent labels and overlap between their fluorescence spectra limit the number of parameters that can be measured in a single analysis.

“There are just so many places along the . . .

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