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Web Date: September 21, 2011

Fast, Reliable Tool Characterizes Antibodies

Biotherapeutics: New method based on mass spectrometry could help drugmakers map antibody-antigen interactions
Department: Science & Technology
News Channels: Analytical SCENE, Biological SCENE
Keywords: Monoclonal antibodies, epitope mapping, mass spectrometry

Small molecules aren’t the only tools drug makers have to target the protein culprits of disease. Antibodies can bind these unruly proteins, to either shut them down or to recruit the body’s immune system to attack the diseased cells. As a result, chemists have turned to so-called therapeutic antibodies more and more to treat diseases such as autoimmune disorders and cancer. Now researchers report a method using mass spectrometry to help drug developers rapidly and . . .

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Chemical & Engineering News
ISSN 0009-2347
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