Advertisement

If you have an ACS member number, please enter it here so we can link this account to your membership. (optional)

ACS values your privacy. By submitting your information, you are gaining access to C&EN and subscribing to our weekly newsletter. We use the information you provide to make your reading experience better, and we will never sell your data to third party members.

ENJOY UNLIMITED ACCES TO C&EN

Analytical Chemistry

Bruker's UltrafleXtreme

by Science, Technology & Education Department
June 11, 2012 | A version of this story appeared in Volume 90, Issue 24

[+]Enlarge
Credit: Bruker
UltrafleXtreme
A photo of the Bruker ultrafleXtreme TOF/TOF mass spectrometer.
Credit: Bruker
UltrafleXtreme

Bruker announced the nano-Advance UHPLC system for capillary and nanoflow separations applications, aimed squarely at the proteomics market. The new system, which builds on Bruker’s acquisition of Michrom, marks the first time that Bruker has offered its own liquid chromatograph. The system includes three pumps, which eliminates the need for split flow and makes the system compatible with two-dimensional LC applications. The system, which was designed to eliminate as much dead volume and gradient delay as possible, can run solvent gradients at flow rates as low as 50 nL/min. The combination of the nano-Advance with Bruker’s CaptiveSpray ion source allows more of the flow coming off the column to enter the mass spectrometer. More peptides and proteins can be analyzed in a single run, which is particularly important for low-abundance proteins. Bruker also announced an updated version of the ultrafleXtreme, its top-of-the-line MALDI time-of-flight (TOF)/TOF mass spectrometer. The instrument now incorporates a 2-kHz laser that improves the acquisition speed and spatial resolution for MALDI imaging. The system can generate multiply charged ions of intact proteins larger than 30,000 daltons.

Article:

This article has been sent to the following recipient:

0 /1 FREE ARTICLES LEFT THIS MONTH Remaining
Chemistry matters. Join us to get the news you need.