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AstraZeneca and FOB Synthesis, a Kennesaw, Ga.-based custom synthesis and antibiotic development firm, will work together to develop combination therapy antibiotics to address drug-resistant infections. The companies will potentially combine AstraZeneca’s preclinical β-lactamase inhibitor (BLI) with carbapenem antibiotics in preclinical studies at FOB. AstraZeneca will develop combinations of its BLI with FOB’s FSI-1671 and FSI-1686 through Phase I, after which it has an option to license the compounds. Financial terms of the deal were not disclosed.
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