Web Date: December 22, 2014
Study Suggests Mechanism For How Eye Protein Protects Against Cataracts
A new study reveals the likely mechanism that a protein called human α-crystallin uses to protect the lens of the eye from clouding or becoming opaque. The work could lead to new drugs to prevent cataract formation.
The human eye lens contains a protein called γD-crystallin that can unfold, oxidize, and aggregate to form cataracts. Human α-crystallin protects the lens by inhibiting γD-crystallin aggregation.
But how this so-called chaperone protein works on a molecular level . . .
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