Chemistry in Pictures: Blue moon | Chemical & Engineering News

Issue Date: March 13, 2018 | Web Date: March 16, 2018

Chemistry in Pictures: Blue moon

Department: Science & Technology
Keywords: Drug discovery, fluorescence
Credit: Constantinos Neochoritis
A photo of a 250 mL flask filled with fluorescent blue powder photographed from the bottom and resembling a moon.
Credit: Constantinos Neochoritis
Credit: Constantinos Neochoritis
A photo of a 250 mL flask tipped on its side containing fluorescent blue powder.
Credit: Constantinos Neochoritis

This quinolinone derivative is just a regular white powder under normal light. But under ultraviolet light, it fluoresces blue. Constantinos Neochoritis, a drug design researcher at the University of Groningen, isolated the derivative contained in this 250 mL flask as part of a project to find molecules that can inhibit specific reactions between proteins. Quinolinone derivatives participate in other types of fluorescence, such as that of South American tree frogs.

Submitted by Constantinos Neochoritis

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