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Pharmaceuticals

FDA approves Sage and Biogen drug for postpartum depression, rejects it for major depressive disorder

by Gina Vitale
August 19, 2023 | A version of this story appeared in Volume 101, Issue 27
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The US Food and Drug Administration has approved Zurzuvae (zuranolone)—the result of a collaboration between Biogen and Sage Therapeutics—as the first oral drug to treat postpartum depression. But the FDA rejected the small molecule for use in major depressive disorder, sending Sage’s stock tanking. In a second-quarter earnings report published after the agency’s decision, Sage CEO Barry Greene said the company is evaluating “pipeline prioritization” and “a workforce reorganization.”

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